Laura Caddoo and VideoJug demonstrate how to make a Brain Shot cocktail -- a layered shooter, creamy and delicious. Southern Comfort, triple sec, and Baileys really do go together! Firstly take a shooter glass, and pour in 15 milliliters or a dash of triple sec. Using the back of a teaspoon, hold it to the edge of the glass. Then pour Baileys over the spoon - a dash or 15 milliliters. And follow this with a final dash of Southern Comfort. And there you have it. Your cocktail is now ready to be served.